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Wenxu Wang#, Wei Chen#, Chaoyang Wu#, Chen Zhang, Jingjing Feng, Pengxiang Liu, Yuru Hu, Hongyun Li, Feng Sun, Kai Jiang, Xinghua Zhang & Zheng Liu*, Hydrogel-based molecular tension fluorescence microscopy for investigating receptor-mediated rigidity sensing. Nature Methods, https://doi.org/10.1038/s41592-023-02037-0 (2023)
中文科普：Link  
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Feng Sun, Hongyun Li, Yuru Hu, Mengsheng Zhang, Wenxu Wang, Wei Chen*, and Zheng Liu* Exploring Mechanical Responses of Cells to Geometric Information Using Micropatterned DNA-Based Molecular Tension Probes
ACS Nano, 17, 18584 (2023)  Link
See C&EN News: Chemistry in Pictures: Cells getting bent out of shape
中文科普：Link 

Yuru Hu, Hongyun Li, Wenxu Wang, Feng Sun, Chaoyang Wu, Wei Chen*, Zheng Liu*, Molecular Force Imaging Reveals that Integrin-dependent Mechanical Checkpoint Regulates Fcγ Receptor-mediated Phagocytosis in Macrophages.
Nano Letters, 23, 5562 (2023)  Link  
中文科普：Link
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Yu-Yao Guo,Yue Gao,Yu-Ru Hu, Yuhan Zhao,Dexiang Jiang,Yulin Wang,Youjing Zhang,Hu Gan,Chang Xie,Zheng Liu, Bo Zhong, Zhi-Dong Zhang*, Jing Yao*, The transient receptor potential vanilloid 2 (TRPV2) channel facilitates virus infection through the Ca2+-LRMDA axis in myeloid cells. Advanced Science, DOI:10.1002/advs.202202857 (2022)
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Liang Wang, Wei Chen*, Hongyun Li, Chaohui Xiong, Feng Sun, Xiaoqing Liu, Yuru Hu, Wenxu Wang, Wenqun Zhong, Zheng Liu*, Exploring integrin-mediated force transmission during confined cell migration by DNA-based tension probes. Analytical Chemistry, DOI:10.1021 (2022)
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Hongyun Li, Chen Zhang, Yuru Hu, Pengxiang Liu, Feng Sun, Wei Chen, Xinghua Zhang, Jie Ma, Wenxu Wang, Liang Wang, Piyu Wu, Zheng Liu*, A Reversible shearing DNA probe for visualizing mechanically strong receptors in living cells. Nature Cell Biology, 23, 642–651 (2021)

NEWS: CHINA SCIENCE DAILY(中国科学报), CAS News, Wuhan University News. 
             小柯生命中文科普： Link 

A step-by-step protocol for the synthesis of the DNA tension probe is provided at Nature Protocol Exchange:

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Hongyun Li, Yuru Hu, Feng Sun, Zheng Liu*,  A reversible shearing DNA-based tension probe for cellular force measurement. Protocol Exchange. https://doi.org/10.21203/rs.3.pex-1451/v1 (2021).

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Yingxue Rong, Wenzhong Yang, Huiwen Hao, Wenxu Wang, Shaozhen Lin, Peng Shi, Yuxing Huang, Bo Li, Yujie Sun, Zheng Liu, Congying Wu,The Golgi microtubules regulate single cell durotaxis,EMBO reports, 2021, In press.

Previous work-----------------------------------

Jing Zhao, Hanquan Su, Gregory E Vansuch, Zheng Liu, Khalid Salaita, R Brian Dyer. Localized Nanoscale Heating Leads to Ultrafast Hydrogel Volume-Phase Transition,ACS Nano, 13, 515–525(2019).
Hanquan Su#, Zheng Liu#, Yang Liu, Victor Pui-Yan Ma, Aaron Blanchard, Jing Zhao , Kornelia Galior, R. Brian Dyer , and Khalid Salaita. Light-Responsive Polymer Particles as Force Clamps for the Mechanical Unfolding of Target Molecules, Nano Letters, 18,2630–2636 (2018)（# co-first author）
Zheng Liu#, Yang Liu#, Yuan Chang, Hamid Reza Seyf, Asegun Henry, Alexa L Mattheyses, Kevin Yehl, Yun Zhang, Zhuangqun Huang, Khalid Salaita. Nanoscale optomechanical actuators for controlling mechanotransduction in living cells, Nature methods, 13, 143-156 (2016)（# co-first author）
Yuan Chang, Zheng Liu, Yun Zhang, Kornelia Galior, Jeffery Yang, Khalid Salaita. "A general approach for generating fluorescent probes to visualize piconewton forces at the cell surface", JACS ,138 (9), 2901-2904 (2016)
 Yang Liu, Lori Blanchfield, Victor Pui-Yan Ma, Rakieb Andargachew, Kornelia Galior, Zheng Liu, Brian Evavold, Khalid Salaita, "DNA-based nanoparticle tension sensors reveal that T-cell receptors transmit defined pN forces to their antigens for enhanced fidelity" Proc. Natl. Acad. Sci. U.S.A, 113 (20), 5610-5615 (2016)
Xiang Wang, Jin-Hui Zhong, Meng Zhang, Zheng Liu, De-Yin Wu, Bin Ren, Revealing Intermolecular Interaction and Surface Restructuring of an Aromatic Thiol Assembling on Au (111) by Tip-Enhanced Raman Spectroscopy, Analytical chemistry, 88 (1), 915-921 (2015)
Yang Liu, Rebecca Medda, Zheng Liu, Kornelia Galior, Kevin Yehl, Joachim P Spatz, Elisabetta Ada Cavalcanti-Adam, Khalid Salaita, Nanoparticle tension probes patterned at the nanoscale: impact of integrin clustering on force transmission, Nano letters, 14 (10), 5539-5546 (2014)
Tao Jiang, Chunfu Xu, Yang Liu, Zheng Liu, Joseph S Wall, Xiaobing Zuo, Tianquan Lian, Khalid Salaita, Chaoying Ni, Darrin Pochan, Vincent P Conticello, Structurally Defined Nanoscale Sheets from Self-Assembly of Collagen-Mimetic Peptides, J. Am. Chem. Soc, 136 (11), 4300-4308 (2014)
Zheng Liu, Haiming Zhu, Nianhui Song, Tianquan Lian, Probing Spatially Dependent Photoinduced Charge Transfer Dynamics to TiO2 Nanoparticles Using Single Quantum Dot Modified Atomic Force Microscopy Tips, Nano letters, 13 (11), 5563-5569 (2013)
Zheng Liu, Allen M Ricks, Haining Wang, Nianhui Song, Fengru Fan, Shengli Zou, Tianquan Lian, High-Resolution Imaging of Electric Field Enhancement and Energy-Transfer Quenching by a Single Silver Nanowire Using QD-Modified AFM Tips. The Journal of Physical Chemistry Letters, 4 (14), 2284-2291 (2013)
Ye Yang, Zheng Liu, Tianquan Lian, Bulk Transport and Interfacial Transfer Dynamics of Photogenerated Carriers in CdSe Quantum Dot Solid Electrodes, Nano letters, 13 (8), 3678-3683 (2013)
Kaifeng Wu, William E Rodríguez-Córdoba, Zheng Liu, Haiming Zhu, Tianquan Lian, Beyond band alignment: hole localization driven formation of three spatially separated long-lived exciton states in CdSe/CdS nanorods, ACS nano, 7 (8), 7173-7185 (2013)
Kaifeng Wu, Zheng Liu, Haiming Zhu, Tianquan Lian, Exciton Annihilation and Dissociation Dynamics in Group II–V Cd3P2 Quantum Dots, The Journal of Physical Chemistry A 117 (29), 6362-6372 (2013)
Nianhui Song, Haiming Zhu, Zheng Liu, Zhuangqun Huang, David Wu, Tianquan Lian, Unraveling the Exciton Quenching Mechanism of Quantum Dots on Antimony-Doped SnO2 Films by Transient Absorption and Single Dot Fluorescence Spectroscopy. ACS nano 7 (2), 1599-1608 (2013)
Kaifeng Wu, Haiming Zhu, Zheng Liu, William Rodríguez-Córdoba, Tianquan Lian, Ultrafast Charge Separation and Long-Lived Charge Separated State in Photocatalytic CdS–Pt Nanorod Heterostructures, J. Am. Chem. Soc, 134 (25), 10337-10340 (2012)
Huiming Xiong, Chun-Ku Chen, Kyungmin Lee, Ryan M Van Horn, Zheng Liu, Bin Ren, Roderic P Quirk, Edwin L Thomas, Bernard Lotz, Rong-Ming Ho, Wen-Bin Zhang, Stephen ZD Cheng, Scrolled polymer single crystals driven by unbalanced surface stresses: rational design and experimental evidence. Macromolecules,  44 (19), 7758-7766 (2011)
Zheng Liu, Song-Yuan Ding, Zhao-Bin Chen, Xiang Wang, Jing-Hua Tian, Jason R Anema, Xiao-Shun Zhou, De-Yin Wu, Bing-Wei Mao, Xin Xu, Bin Ren, Zhong-Qun Tian, Revealing the molecular structure of single-molecule junctions in different conductance states by fishing-mode tip-enhanced Raman spectroscopy, Nature communications 2, 305 (2011)
Zheng Liu, Xiang Wang, Ke Dai, Shan Jin, Zhi-Cong Zeng, Mu‐De Zhuang, Zhi-Lin Yang, De-Yin Wu, Bin Ren, Zhong-Qun Tian, Tip-enhanced Raman spectroscopy for investigating adsorbed nonresonant molecules on single-crystal surfaces: tip regeneration, probe molecule, and enhancement effect, Journal of Raman Spectroscopy 40 (10), 1400-1406 (2009)
Xi Wang, Zheng Liu, Mu-De Zhuang, Hai-Ming Zhang, Xiang Wang, Zhao-Xiong Xie, De-Yin Wu, Bin Ren, Zhong-Qun Tian, Tip-enhanced Raman spectroscopy for investigating adsorbed species on a single-crystal surface using electrochemically prepared Au tips, Applied Physics Letters. 91 (10), 101105 (2007)
Zheng Liu, Zhi-Lin Yang, Li Cui, Bin Ren, Zhong-Qun Tian, Electrochemically roughened palladium electrodes for surface-enhanced Raman spectroscopy: Methodology, mechanism, and application. The Journal of Physical Chemistry C. 111 (4), 1770-1775 (2007)
Li Cui, Zheng Liu, Sai Duan, De-Yin Wu, Bin Ren, Zhong-Qun Tian, Shou-Zhong Zou, Orientation change of adsorbed pyrazine on roughened rhodium electrodes as probed by surface-enhanced Raman spectroscopy. The Journal of Physical Chemistry B. 109 (37), 17597-17602 (2005)
Jia-Wen Hu, Yong Zhang, Jian-Feng Li, Zheng Liu, Bin Ren, Shi-Gang Sun, Zhong-Qun Tian, Tim Lian. Synthesis of Au@ Pd core–shell nanoparticles with controllable size and their application in surface-enhanced Raman spectroscopy. Chemical physics letters. 408 (4), 354-359 (2005)
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